Antibodies

MOUSE ANTI RAT CD49d:FITC

Manufacturer GENWAY
Category Products / Antibody
Type Antibody
Specific against Rat
Amount 0.1 mg
Host Mouse
ArtNr 20-783-314745
Available
Genway ID:
GWB-1864F2
Specificity:
CD49d
Isotype:
IgG2a
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09% Sodium Azide (NaN3) 1% Bovine Serum AlbuminApprox. Protein Concentrations: IgG concentration 0. 1mg/ml
Immunogen:
RBL-2H3 rat basophilic leukaemia cell line.
Specificity:
Specifically recognises rat CD49d otherwise known as integrin alpha 4 chain/VLA-4 a 150kDa type-1 transmembrane glycoprotein and member of the integrin alpha chain family which acts as a receptor for fibronectin and CD106 (VCAM-1). CD49d is expressed broadly on T and B lymphocytes monocytes thymocytes mast cells and dendritic cells and is involved in cell-cell interactions mononuclear cell trafficking to sites of endothelial inflammation and the adhesion of cells to the extracellular matrix. Clone MRalpha4-1 inhibits the in vitro and in vivo functions of CD49d(1). Studies have shown that in rat Peyer\' s patches clone MRalpha4-1 inhibits the rolling and adherence of lymphocytes to postcapillary venules (PCV) and significantly inhibits the transendothelial migration of T lymphocytes(2). Recommended for functional studies. Recommended Negative Controls: MOUSE IgG2a NEGATIVE CONTROL:FITC
Amount: 0.1 mg
Available: In stock
Listprice: €419.29
Price: €419.29
lieferbar

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