Antibodies

MOUSE ANTI RAT CD86:FITC

Manufacturer GENWAY
Category
Type Antibody
Specific against Rat
Amount 0.1 mg
Host Mouse
ArtNr 20-783-314749
Available
Genway ID:
GWB-2C8080
Specificity:
CD86
Isotype:
IgG1
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09% Sodium Azide (NaN3) 1% Bovine Serum AlbuminApprox. Protein Concentrations: IgG concentration 0. 1mg/ml
Immunogen:
HTLV-1 transformed Lewis-S1 cells
Specificity:
Specifically recognises rat CD86 otherwise known as B7-2 a type I transmembrane protein and member of the Ig superfamily which acts as a ligand for both CD28 and CD152 (CTLA-4) and is primarily expressed on antigen presenting cells (APCs) including dendritic cells and also on germinal centre B cells and macrophages. Like CD80 CD86 is an accessory molecule which functions in the CD28-CD80/CD86 co-stimulatory pathway vital for T cell activation crosstalk between T and B cells and Th2-mediated Ig production. Clone 24F has been shown to block the co-stimulatory activity of rat CD86. AbD Recommended Negative Controls: MOUSE IgG1 NEGATIVE CONTROL:FITC
Amount: 0.1 mg
Available: In stock
Listprice: €368.39
Discount: -10.0%
Price: €331.55
You save: €36.84
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