MOUSE ANTI RAT MHC CLASS II RT1Bu/l

Manufacturer GENWAY
Category
Type Antibody
Specific against Rat
Amount 0.1 mg
Host Mouse
ArtNr 20-783-314776
Available
Genway ID:
GWB-8E8D42
Specificity:
MHC CLASS II RT1Bu/l
Isotype:
IgG1Species Cross Reactivity: Reacts with: MouseN. B. Antibody reactivity and working conditions may vary between species.
Preparation:
Purified IgG prepared by ion exchange chromatography from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09% Sodium AzideApprox. Protein Concentrations: IgG concentration 1. 0 mg/ml
Immunogen:
Rat thymocyte membrane glycoproteins
Specificity:
The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In rats this complex is referred to as the RT1 region. In mice this complex is referred to as the H-2 region.
Specificity:
Recognises a polymorphic determinant of the rat RT1B MHC class II antigen reacting with haplotypes u and l. The literature reports reactivity with Lewis Wistar and AO strain rats but not BN DA or PVG/c strains (1 2). This antibody is useful for distinguishing RT1B positive cells from different rat strains e. g. for recognising cells of donor origin in bone marrow reconstituted radiation chimaeras (3 4).
Specificity:
Also cross reacts with mouse strains of the H-2 haplotypes b and s. Analysis of recombinant mouse strains has mapped the OX-3 determinant to the H-2I-A region. This product is routinely tested in flow cytometry on Lewis rat splenocytes. Recommended Negative Controls: MOUSE IgG1 NEGATIVE CONTROLRecommended Secondary Antibodies: Rabbit Anti Mouse IgGGoat Anti Mouse IgGGoat Anti Mouse IgG (H/L)Goat Anti Mouse IgG IgA IgMHuCAL Anti Mouse IgG1Goat Anti Mouse IgG (Fc)Sheep Anti Mouse IgG (H/L)
Amount: 0.1 mg
Available: In stock
Listprice: €212.88
Discount: -10.0%
Price: €191.59
You save: €21.29
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