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Cyclopamine

Cyclopamine

Item no.	HY-17024-500mg
Manufacturer	MedChem Express
CASRN	4449-51-8
Amount	500 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 g 1 mg 200 mg 25 mg 500 mg 50 mg 5 mg
Specific against	other
Purity	99.97
Smiles	CC1=C2[C@@]([C@@]3([H])[C@]([C@@]4(C(C[C@@H](O)CC4)=CC3)C)([H])C2)([H])CC[C@@]15[C@@H]([C@@]6([H])[C@](C[C@H](C)CN6)([H])O5)C
Alias	11-Deoxojervine
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Endogenous Metabolite; Hedgehog; Smo
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	411.62
Product Description	Cyclopamine is a Hedgehog (Hh) pathway antagonist with an IC50 of 46 nM in the Hh cell assay. Cyclopamine is also a selective Smo inhibitor.
Manufacturer - Research Area	Cancer
Solubility	DMSO : 10 mg/mL (ultrasonic; warming; heat to 80°C)\|Ethanol : 20 mg/mL (ultrasonic)
Manufacturer - Pathway	Metabolic Enzyme/Protease; Stem Cell/Wnt
Clinical information	No Development Reported
Isoform	Human Endogenous Metabolite

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