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PACOCF3

PACOCF3

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	1mg(32.42mM*100uLinEthanol)
Item no.	HY-108607-1mg(32.42mM*100uLinEthanol)
CASRN	141022-99-3
Available
Product Description	PACOCF3 (Palmityltrifluoromethylketone) is a selective phospholipase A2 inhibitor with an IC50 of 3.8 μM. PACOCF3 alters Ca2+ signaling in renal tubular cells.
StorageTemperature	Solution, -20°C, 2 years
Applications	COVID-19-immunoregulation
Formula	C17H31F3O
References	[1].E J Ackermann, et al. Inhibition of macrophage Ca(2+)-independent phospholipase A2 by bromoenol lactone and trifluoromethyl ketones. J Biol Chem. 1995 Jan 6; 270(1):445-50. \| [2].C R Jan, et al. Dual action of palmitoyl trifluoromethyl ketone (PACOCF3) on Ca2+ signaling: activation of extracellular Ca2+ influx and alteration of ATP- and bradykinin-induced Ca2+ responses in Madin Darby canine kidney cells. Arch Toxicol. 2000 Oct; 74(8):447-51.
MolecularWeight	308.42
Research Area	Inflammation/Immunology
Target	Phospholipase
Isoform	PLA2
Pathway	Metabolic Enzyme/Protease

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Amount: 1mg(32.42mM*100uLinEthanol)

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Delivery expected until 4/20/2023

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