« Back
Home /
GRK6-IN-1

GRK6-IN-1

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	25mg
Item no.	HY-142812-25mg
CASRN	2677786-61-5
Available
Product Description	GRK6-IN-1 (compound 18) is a potent inhibitor of G protein-coupled receptor kinase 6 (GRK6) with an IC50 of 120 nM. GRK6 is a critical kinase required for the survival of multiple myeloma (MM) cells. GRK6-IN-1 has the potential for the research of multiple myeloma.
StorageTemperature	Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Applications	Cancer-Kinase/protease
Formula	C22H23ClN6O2
References	[1].Uehling DE, et al. Design, Synthesis, and Characterization of 4-Aminoquinazolines as Potent Inhibitors of the G Protein-Coupled Receptor Kinase 6 (GRK6) for the Treatment of Multiple Myeloma [published correction appears in J Med Chem. 2022 Jan 13; 65(1):886-887]. J Med Chem. 2021; 64(15):11129-11147.
MolecularWeight	438.91
Research Area	Cancer
Solubility	DMSO : 50 mg/mL (113.92 mM; Need ultrasonic)
Target	Others
Pathway	Others

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 25mg

available

Delivery expected until 4/13/2023

Compare

Add to wishlist

Recommend by mail

Request delivery time

Ask a technical question