« Back
Home /
Melphalan

Melphalan

Manufacturer	MedChem Express
Category	Oncology Food Safety Allergenes Inhibitors & Compound Libraries Small Molecules By Organ Skin Cancer Head & Neck Cancer Heart & Blood Cancer
Type	Inhibitors
Specific against	other
Clone	N/A
Amount	10mM*1 mL
Item no.	HY-17575-10mM
eClass 6.1	30220300
eClass 9.0	32160605
Available
Synonyms	L-PAM
MW	3052002
Solubility	DMSO ? 9.2 mg/mL
Biological Description	Melphalan(Sarcolysin; L-PAM) is a chemotherapy drug belonging to the class of nitrogen mustard alkylating agents; attaches the alkyl group to the guanine base of DNA. IC50 value: Target: DNA alkylator The agent was first investigated as a possible drug for use in melanoma. It was not found to be effective, but has been found to be effective in the treatment of myeloma. Melphalan is currently being used to treat ocular retinoblastoma, a pediatric solid tumor. This is accomplished via transarterial catheter based slow pulsed infusion into the ophthalmic artery.[
Publications	Cell Oncol (Dordr). 2016 Dec; 39(6):511-522.
Free Sample	Available in quantities of 0, 5mg-1mg. Three different samples per customer per year!
Journal	Chen P, et al. The functional status of DNA repair pathways determines the sensitization effect to cisplatin in non-small cell lung cancer cells. Cell Oncol (Dordr). 2016 Dec; 39(6):511-522.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

HY-17575-10mM-safety-datasheet.pdf