Yoda 1

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	10mM/1mL
Item no.	HY-18723-10mM
Targets	Others
CASRN	448947-81-7
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	Yoda 1 is a potent and selective Piezo1 agonist. Yoda 1 activates purified Piezo1 channels. Yoda 1 potently inhibits macropinocytosis induced by epidermal growth factor (EGF). Yoda 1 enhances Ca2+ influx followed by activation of the calcium-activated potassium channel KCa3.1 and inhibition of Rac1 activation[1][2][3].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	355.27
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cardiovascular Disease
Solubility	DMSO : 15.62 mg/mL (ultrasonic; warming; heat to 60°C)\|Ethanol : 5 mg/mL (ultrasonic)
Manufacturers Target	Akt; ERK; Piezo Channel; Potassium Channel
Isoform	ERK1; ERK2
Pathway	MAPK/ERK Pathway; Membrane Transporter/Ion Channel; PI3K/Akt/mTOR; Stem Cell/Wnt
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

HY-18723-10mM-safety-datasheet.pdf