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rg-7112

rg-7112

Item no.	V0045-25mg
Manufacturer	InvivoChem LLC
CASRN	939981-39-2
Amount	25mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0045CAS #:939981-39-2Purity >=98% Description: RG7112 (also known as RO5045337) is a novel, potent and highly selective antagonist/inhibitor of the p53-MDM2 protein-protein interaction with IC50 of 11 nM. RG-7112 is under clinical development for cancer treatment. Description: References: Pediatr Blood Cancer. 2013 Apr; 60(4):633-41. Exp Hematol. 2014 Feb; 42(2):137-45.e5. References:
Molecular Weight (MW)	727.78
Formula	C38H48Cl2N4O4S
CAS No.	939981-39-2
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 100 mg/mL (137.7 mM)
	Water:< 1 mg/mL (slightly soluble or insoluble)
	Ethanol: N/A
Solubility (In vivo)	1% CMC Na:14 mg/mL
Chemical Name	[(4S, 5R)-2-(4-tert-butyl-2-ethoxyphenyl)-4, 5-bis(4-chlorophenyl)-4, 5-dimethylimidazol-1-yl]-[4-(3-methylsulfonylpropyl)piperazin-1-yl]methanone
Synonym	RG7112; RG-7112; RG 7112; RO5045337; RO 5045337; RO5045337

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25mg

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