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CYP3A4 Knockout 293T Cell Lysate

CYP3A4 Knockout 293T Cell Lysate

Manufacturer	Abclonal
Category	Cell Lines & Cell Culture Cell Lysates
Specific against	other
Applications	WB
Amount	100 ug
Item no.	RM02262-100ug
Available
protein size	CYP3A4
GeneID(Human)	1576
Route	CYP3A4 KO cell lysate and WT cell lysate.
Imminogen	4℃
Storage	Lysate is stable for 12 months when stored at -20℃. Minimizing freeze-thaw cycles.
BackGround	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Feb 2011]
RecommandDilutionA	1 vial parental cell Lysate and 1 vial knockout cell Lysate
ProteinWeight	CYP3A4
AntigenSeq	To be used as WB control. Lysate is supplied in 1× SDS sample buffer (2% SDS, 60 mM Tris-HCl pH 6.8, 10% Glycerol, 0.02% Bromophenol blue, 60 mM beta-mercaptoethanol). Lysate should be boiled for 3 - 5 minutes before loading onto gel.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

available

Delivery expected until 6/22/2023