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GFRA1 Knockout 293T Cell Lysate

GFRA1 Knockout 293T Cell Lysate

Manufacturer	Abclonal
Category	Cell Lines & Cell Culture Cell Lysates
Specific against	other
Applications	WB
Amount	100 ug
Item no.	RM02479-100ug
Available
protein size	GFRA1
GeneID(Human)	2674
Route	GFRA1 KO cell lysate and WT cell lysate.
Imminogen	4℃
Storage	Lysate is stable for 12 months when stored at -20℃. Minimizing freeze-thaw cycles.
BackGround	This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
RecommandDilutionA	1 vial parental cell Lysate and 1 vial knockout cell Lysate
ProteinWeight	GFRA1
AntigenSeq	To be used as WB control. Lysate is supplied in 1× SDS sample buffer (2% SDS, 60 mM Tris-HCl pH 6.8, 10% Glycerol, 0.02% Bromophenol blue, 60 mM beta-mercaptoethanol). Lysate should be boiled for 3 - 5 minutes before loading onto gel.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

available

Delivery expected until 7/27/2023