Comparison

Rabbit anti-Human IL-2 mAb (CAP)

Manufacturer Abclonal
Category
Type Antibody Monoclonal
Specific against other
Isotype IgG
Applications ELISA
Amount 1000 ug
Item no. RM17589-1000ug
eClass 6.1 32160702
eClass 9.0 42030590
Available
Description

Human IL-2 Sanwich ELISA Immunoassay

  Recommended
Concentration
Sample
ELISA Capture
Background
Interleukin-2 (IL-2) is an interleukin, a type of cytokine immune system signaling molecule, which is a leukocytotrophic hormone that is instrumental in the body’s natural response to microbial infection and in discriminating between foreign (non-self) and self. IL-2 mediates its effects by binding to IL-2 receptors, which are expressed by lymphocytes, the cells that are responsible for immunity. Mature human IL-2 shares 56% and 66% aa sequence identity with mouse and rat IL-2, respectively. Human and mouse IL-2 exhibit crossspecies activity. The receptor for IL-2 consists of three subunits that are present on the cell surface in varying preformed complexes. IL-2 is also necessary during T cell development in the thymus for the maturation of a unique subset of T cells that are termed regulatory T cells (T-regs). After exiting from the thymus, T-Regs function to prevent other T cells from recognizing and reacting against “self antigens”, which could result in “autoimmunity”. T-Regs do so by preventing the responding cells from producing IL-2. Thus, IL-2 is required to discriminate between self and non-self, another one of the unique characteristics of the immune system.
Manufacturers Category
Elisa Antibody Kit
Immunogen
Recombinant IL-2 Protein
Isotype Information
Rabbit IgG
Storage
This antibody can be stored at 2℃-8℃ for one monthwithout detectable loss of activity. Antibody products are stable for twelve months fromdate of receipt when stored at -20℃ to -80℃. Preservative-Free.
Recommended Dilution
< 1.0 EU/μg of the protein by LAL method.
Protein Size
Primary antibody

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1000 ug
Available: In stock
available

Delivery expected until 4/30/2024 

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