Comparison

Recombinant Mouse IL-1 R1/IL-1 RI Protein

Manufacturer Abclonal
Category
Type Proteins Recombinant
Specific against other
Amount 1000 ug
Item no. RP00728-1000ug
eClass 6.1 34160400
eClass 9.0 42020190
Available
AntigenSeq
LEIDVCTEYPNQIVLFLSVNEIDIRKCPLTPNKMHGDTIIWYKNDSKTPISADRDSRIHQQNEHLWFVPAKVEDSGYYYCIVRNSTYCLKTKVTVTVLENDPGLCYSTQATFPQRLHIAGDGSLVCPYVSYFKDENNELPEVQWYKNCKPLLLDNVSFFGVKDKLLVRNVAEEHRGDYICRMSYTFRGKQYPVTRVIQFITIDENKRDRPVILSPRNETIEADPGSMIQLICNVTGQFSDLVYWKWNGSEIEWND
BackGround
Mouse Interleukin-1 receptor type 1/IL-1 RI is a cytokine receptor that belongs to the interleukin-1 receptorfamily. This protein is a receptor for interleukin 1 alpha (IL1A), interleukin 1 beta (IL1B), and interleukin 1receptor antagonist (IL1RA). It is an important mediator involved in many cytokine induced immune andinflammatory responses. An IL1 receptor accessory protein that can heterodimerize with the Type I receptor inthe presence of IL1α or IL1β but not IL1ra, was identified. This Type I receptor complex appears to mediate allthe known IL1 biological responses. The receptor Type II has a short cytoplasmic domain and does nottransduce IL1 signals. In addition to the membranebound form of IL1 RII, a naturallyoccurring soluble form ofIL1 RII has been described. It has been suggested that the Type II receptor, either as the membranebound or asthe soluble form, serves as a decoy for IL1 and inhibits IL1 action by blocking the binding of IL1 to the signalingType I receptor complex.
Cross-Reactivity
Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.
GeneSymbol
IL-1 RI
Imminogen
Leu20-Lys338
ProteinDescription
Recombinant Mouse IL-1 R1/IL-1 RI Protein is produced by Human Cells expression system. The target protein is expressed with sequence (Leu20-Lys338) of mouse IL-1 R1/IL-1 RI (Accession #P13504) fused with an Fc tag at the C-terminus.
ProteinFormulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.Contact us for customized product form or formulation.
RecommandDilutionA
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.Contact us for customized product form or formulation.
Route
C-Fc
Storage
Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1000 ug
Available: In stock
available

Delivery expected until 4/30/2024 

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