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Cynomolgus DR3 / TNFRSF25 Protein, Fc Tag

Cynomolgus DR3 / TNFRSF25 Protein, Fc Tag

Item no.	TN5-C5257-100ug
Manufacturer	ACROBiosystems
Amount	100 ug
Quantity options	100 ug 200 ug x 5
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Solid
Specific against	Monkey (Cynomolgus, Simian)
Host	HEK293
Conjugate/Tag	Unconjugated, Fc
Purity	90%
Citations	(1) Kitson J., et al., 1996, Nature 384:372-375. (2) Bodmer J.-L., et al., 1997, Immunity 6:79-88. (3) Marsters S.A., et al., 1996, Curr. Biol. 6:1669-1676.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	TNFRSF25,DR3,APO3,DDR3,TNFRSF12,WSL,WSL1
Shipping Condition	Room temperature
Available
Specificity	Cynomolgus
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	C-Fc, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	46.3 kDa
Manufacturer - Format	Powder
Description	Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) is also known as Apo-3, Death receptor 3 (DDR3 or DR3), Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor TRAMP, Lymphocyte-associated receptor of death, Apo-3, which is a member of the TNF-receptor superfamily. TNFRSF25 is a homodimer protein, which can Interact strongly via the death domains with TNFRSF1 and TRADD to activate at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling. TNFRSF25 is receptor for TNFSF12 / APO3L / TWEAK.
Background	Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) is also known as Apo-3, Death receptor 3 (DDR3 or DR3), Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor TRAMP, Lymphocyte-associated receptor of death, Apo-3, which is a member of the TNF-receptor superfamily. TNFRSF25 is a homodimer protein, which can Interact strongly via the death domains with TNFRSF1 and TRADD to activate at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling. TNFRSF25 is receptor for TNFSF12 / APO3L / TWEAK.
Molecule	DR3
Exp Region	Gln 20 - Gly 203
Characteristics	This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 46.3 kDa. The protein migrates as 50-60 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	Tris with Glycine, Arginine and NaCl, pH7.5
Stability	● -20°C to -70°C for 12 months in lyophilized state ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

TN5-C5257-100ug-datasheet.pdf

TN5-C5257-100ug-safety-datasheet.pdf