Comparison

Anti-Acetyllysine Rabbit pAb (BSA and Azide Free)

Item no. PTM-132
Manufacturer PTM Biolabs
Amount 100 ug
Format Lyophilized powder
Applications WB, FC
Specific against other
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
Alias Kac
Shipping condition Room temperature
Available
Manufacturer - Type
Primary Antibodies
Manufacturer - Category
Pan PTM Antibodies
Storage Conditions
Before reconstitution, centrifuge the vial at 12, 000 x g for 20 seconds. Add sterile, deionized water to achieve a final antibody concentration of 1 mg/ml. The antibody is now in 1X PBS solution. Aliquot and store at -80°C. Avoid freeze/thaw cycles.
Molecular Weight
Multiple
Manufacturer - Research Area
Post-Translational Modificaiton
Manufacturer - Reactivity
All
Purification Method
Protein A and immunogen affinity purified
Manufacturer - Specificity
Anti-Acetyllysine Rabbit pAb (BSA and Azide Free) detects proteins post-translationally modified by Acetylation on lysine residues. This pan antibody recognizes Acetylated lysine independent of its surrounding sequences.
Constituents
PBS
PTM
Acetyl
Modification Site
Lys
Immunogen
Acetylated lysine peptides
Clonality
Polyclonal
Stability
Stable for 12 months from date of receipt/reconstitution.
Background
Histone post-translational modifications (PTMs) are key mechanisms of epigenetics that modulate chromatin structures, termed as “histone code”. The PTMs on histone including acetylation, methylation, phosphorylation and novel acylations directly affect the accessibility of chromatin to transcription factors and other epigenetic regulators, altering genome stability, gene transcription, etc. Histone acetylation occurs primarily at multiple lysine residues on the amino-terminal of core histones, in response to various stimuli and plays vital roles in the regulation of gene expression, DNA damage repair, chromatin dynamics, etc. Mostly, histone H2A is primarily acetylated at Lys5, 9, 15, and 36; H2B is primarily acetylated at Lys5, 12, 15, 16, and 20. Histone H3 is primarily acetylated at Lys4, 9, 14, 18, 23, 27, 56, and 79. Histone H4 is primarily acetylated at Lys5, 8, 12, 16, and 20. Histone acetyltransferases (HATs) and histone deacetylases (HDACs) are major regulating factors.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
available

Delivery expected until 1/3/2025 

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