Anti-PDGFR alpha Mouse mAb

Primary Antibodies

PDGFR alpha

Store at -20°C. Avoid freeze/thaw cycles.

CD140a is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. CD140a plays a role in organ development, wound healing, and tumor progression. Mutations in CD140a gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

PBS, Glycerol, BSA

Recombinant Monoclonal

CD140a is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. CD140a plays a role in organ development, wound healing, and tumor progression. Mutations in CD140a gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.