Item no. |
PTM-6784 |
Manufacturer |
PTM Biolabs
|
Amount |
100 ul |
Format |
Lyophilized powder |
Applications |
WB, IHC-P |
Specific against |
Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus) |
Host |
Rabbit |
Isotype |
IgG |
Conjugate/Tag |
Unconjugated |
Alias |
Neuromodulin, Growth-associated protein 43, Neural phosphoprotein B-50, pp46 |
Shipping condition |
Room temperature |
Available |
|
Manufacturer - Type |
Primary Antibodies |
Manufacturer - Category |
Uncategorized |
Manufacturer - Targets |
GAP43 |
Shipping Temperature |
Ambient temperature |
Storage Conditions |
Store at -20°C. Avoid freeze/thaw cycles. |
Manufacturer - Research Area |
Neuroscience |
Product description |
GAP43, also known as neuromodulin, B-50, P-57, F1 and pp46, is a neuronal growth-associated protein. Deficiency of GAP43 in mice results in death early in the postnatal period. GAP43 also is one of the main substrates for protein kinase C in the brain. GAP43 is an intracellular growth-associated protein that appears to assist neuronal pathfinding and branching during development and regeneration, and may contribute to presynaptic membrane changes in the adult, leading to the neurotransmitter release, endocytosis and synaptic vesicle recycling, long-term potentiation, spatial memory formation, and learning. |
Purification Method |
Protein A and immunogen affinity purified |
Constituents |
PBS, Glycerol, BSA |
PTM |
Unmodified |
Clonality |
Polyclonal |
Stability |
Stable for 12 months from date of receipt/reconstitution. |
Background |
GAP43, also known as neuromodulin, B-50, P-57, F1 and pp46, is a neuronal growth-associated protein. Deficiency of GAP43 in mice results in death early in the postnatal period. GAP43 also is one of the main substrates for protein kinase C in the brain. GAP43 is an intracellular growth-associated protein that appears to assist neuronal pathfinding and branching during development and regeneration, and may contribute to presynaptic membrane changes in the adult, leading to the neurotransmitter release, endocytosis and synaptic vesicle recycling, long-term potentiation, spatial memory formation, and learning. |
Cellular Localization |
Cytoplasm, membrane |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.