Item no. |
PTM-6807 |
Manufacturer |
PTM Biolabs
|
Amount |
100 ul |
Format |
Lyophilized powder |
Applications |
IHC-P |
Specific against |
Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus) |
Host |
Rabbit |
Isotype |
IgG |
Conjugate/Tag |
Unconjugated |
Alias |
Carbonic anhydrase 9, Carbonate dehydratase IX, Membrane antigen MN homolog, CAIX |
Shipping condition |
Room temperature |
Available |
|
Manufacturer - Type |
Primary Antibodies |
Manufacturer - Category |
Uncategorized |
Manufacturer - Targets |
Carbonic Anhydrase 9 / CA9 |
Shipping Temperature |
Ambient temperature |
Storage Conditions |
Store at -20°C. Avoid freeze/thaw cycles. |
Manufacturer - Research Area |
Cardiovascular Biology, Signal Transduction, Cancer, Metabolism |
Product description |
CAIX, also named as CA9, is a transmembrane protein. It is one of only two tumor-associated carbonic anhydrase isoenzymes known. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CAIX is expressed in all clear-cell renal cell carcinoma but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. |
Purification Method |
Protein A and immunogen affinity purified |
Constituents |
PBS, Glycerol, BSA |
PTM |
Unmodified |
Clonality |
Polyclonal |
Stability |
Stable for 12 months from date of receipt/reconstitution. |
Background |
CAIX, also named as CA9, is a transmembrane protein. It is one of only two tumor-associated carbonic anhydrase isoenzymes known. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CAIX is expressed in all clear-cell renal cell carcinoma but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. |
Cellular Localization |
Nucleus, Cell membrane, Cell projection |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.