Anti-PDX1 Rabbit pAb

Primary Antibodies

PDX1

Store at -20°C. Avoid freeze/thaw cycles.

The pancreatic duodenal homeobox gene-1 (PDX1) is a transcription factor that contributes to pancreas development, pancreatic β-cell differentiation, and mature β-cell function. It plays an essential role in the commitment of endoderm to a pancreatic and later β-cell phenotype. In the mature pancreas, PDX1 expression is more restricted to the pancreatic β-cells, where it promotes the expression of genes important for β-cell functions such as insulin, glucokinase, and Glut2. Mutations of the corresponding PDX1 gene may be associated with diabetes and cases of pancreatic insufficiency.

PBS, Glycerol, BSA

Polyclonal

The pancreatic duodenal homeobox gene-1 (PDX1) is a transcription factor that contributes to pancreas development, pancreatic β-cell differentiation, and mature β-cell function. It plays an essential role in the commitment of endoderm to a pancreatic and later β-cell phenotype. In the mature pancreas, PDX1 expression is more restricted to the pancreatic β-cells, where it promotes the expression of genes important for β-cell functions such as insulin, glucokinase, and Glut2. Mutations of the corresponding PDX1 gene may be associated with diabetes and cases of pancreatic insufficiency.