Comparison

Anti-Rab5A Rabbit mAb

Item no. PTM-6958
Manufacturer PTM Biolabs
Amount 100 ul
Format Lyophilized powder
Applications WB
Clone JMMR-3668
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG Kappa
Conjugate/Tag Unconjugated
Alias Ras-related protein Rab-5A, RAB5
Shipping condition Room temperature
Available
Manufacturer - Type
Primary Antibodies
Manufacturer - Category
Uncategorized
Manufacturer - Targets
Rab5A
Shipping Temperature
Ambient temperature
Storage Conditions
Store at -20°C. Avoid freeze/thaw cycles.
Manufacturer - Research Area
Signal Transduction, Neuroscience
Product description
Rab5 is a member of the Ras superfamily of small Rab GTPases. Rab5 is localized at the plasma membrane and early endosomes and functions as a key regulator of vesicular trafficking during early endocytosis. The conformational change between Rab5 GTP/GDP states is essential for its biological function as a rate limiting regulator at multiple steps during endocytosis. Rab5 exerts its function by interacting with several Rab5-specific effectors. These proteins form complexes with Rab5 on a specialized Rab domain of the endosome and promote recycling of Rab5-cargo targets between endosome and the plasma membrane.
Purification Method
Protein A purified
Constituents
PBS
PTM
Unmodified
Clonality
Recombinant Monoclonal
Stability
Stable for 12 months from date of receipt/reconstitution.
Background
Rab5 is a member of the Ras superfamily of small Rab GTPases. Rab5 is localized at the plasma membrane and early endosomes and functions as a key regulator of vesicular trafficking during early endocytosis. The conformational change between Rab5 GTP/GDP states is essential for its biological function as a rate limiting regulator at multiple steps during endocytosis. Rab5 exerts its function by interacting with several Rab5-specific effectors. These proteins form complexes with Rab5 on a specialized Rab domain of the endosome and promote recycling of Rab5-cargo targets between endosome and the plasma membrane.
Cellular Localization
Membrane, Cytoplasm, Melanosome, Phagosome, Endosome

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
available

Delivery expected until 1/3/2025 

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close