Comparison

Anti-TIP49A Rabbit pAb

Item no. PTM-6975
Manufacturer PTM Biolabs
Amount 100 ul
Format Lyophilized powder
Applications WB, IHC-P
Specific against Human, Mouse
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
Alias RuvB-like 1, ECP-54, NMP 238, Pontin 52
Shipping condition Room temperature
Available
Manufacturer - Type
Primary Antibodies
Manufacturer - Category
Uncategorized
Manufacturer - Targets
TIP49A
Shipping Temperature
Ambient temperature
Storage Conditions
Store at -20°C. Avoid freeze/thaw cycles.
Manufacturer - Research Area
Epigenetics
Product description
TIP49A is also named as RUVBL1, is a member of the AAA (ATPase associated with diverse cellular activities) family of proteins that is associated with several chromatin-remodelling complexes and has important roles in transcriptional regulation, the DNA damage response, telomerase activity, snoRNP assembly, cellular transformation and cancer metastasis. It consists of 456 amino acids (50 kDa) and interacts with TATA-binding protein (TBP), which is a central component for transcriptional regulation by forming complexes with various transcription regulators. TIP49A is a component of a large nuclear protein complex, possibly the RNA polymerase II holoenzyme. TIP49A is also highly homologous to RuvB proteins that function as a DNA helicase promote branch migration of the Holliday junction.
Purification Method
Protein A and immunogen affinity purified
Constituents
PBS, Glycerol, BSA
PTM
Unmodified
Clonality
Polyclonal
Stability
Stable for 12 months from date of receipt/reconstitution.
Background
TIP49A is also named as RUVBL1, is a member of the AAA (ATPase associated with diverse cellular activities) family of proteins that is associated with several chromatin-remodelling complexes and has important roles in transcriptional regulation, the DNA damage response, telomerase activity, snoRNP assembly, cellular transformation and cancer metastasis. It consists of 456 amino acids (50 kDa) and interacts with TATA-binding protein (TBP), which is a central component for transcriptional regulation by forming complexes with various transcription regulators. TIP49A is a component of a large nuclear protein complex, possibly the RNA polymerase II holoenzyme. TIP49A is also highly homologous to RuvB proteins that function as a DNA helicase promote branch migration of the Holliday junction.
Cellular Localization
Cytoplasm, Nucleus

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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