Anti-Citrulline-NPM1 (Arg196) Rabbit pAb

Primary Antibodies

NPM1

Store at -20°C. Avoid freeze/thaw cycles.

Nucleophosmin (NPM1) is a putative ribosome assembly factor with a high affinity for peptides containing nuclear localization signals (NLSs). The transport of proteins across the nuclear envelope is a selective, multistep process involving several cytoplasmic factors. Proteins must be recognized as import substrates, dock at the nuclear pore complex and translocate across the nuclear envelope in an ATP-dependent fashion. Several cytosolic and nuclear proteins that are central to this process have been identified. NPM1 is involved in ribosomal assembly and rRNA transport. It is highly phosphorylated by Cdc2 kinase during mitosis.

PBS, Glycerol, BSA

Arg196

Stable for 12 months from date of receipt/reconstitution.

Nucleus, nucleoplasm