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Recombinant Human Interleukin-4(IL4)

Recombinant Human Interleukin-4(IL4)

Hersteller	Cusabio
Kategorie	Neuroscience Neural Adhesion Molecules Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Specific against	other
Menge	200ug
Host	E.coli
ArtNr	CSB-RP067374h-200
eClass 6.1	34160400
eClass 9.0	42020190
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Research Topic	Immunology
Uniprot ID	P05112
Gene Names	IL4
Organism	Homo sapiens (Human)
AA Sequence	HKCDITLQEIIKTLNSLTEQKTLCTELTVTDIFAA SKNTTEKETFCRAATVLRQFYSHHEKDTRCLGATA QQFHRHKQLIRFLKRLDRNLWGLAGLNSCPVKEAN QSTLENFLERLKTIMREKYSKCSS
Expression Region	25-153aa
Sequence Info	Full Length of Mature Protein
Source	E.coli
Tag Info	N-terminal 6xHis-tagged
MW	19 kDa
Alternative Name(s)	B-cell stimulatory factor 1 ; BSF-1Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra
Relevance	Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.
Reference	Polymorphism in the P-selectin and interleukin-4 genes as determinants of stroke a population-based, prospective genetic analysis.Zee R.Y.L., Cook N.R., Cheng S., Reynolds R., Erlich H.A., Lindpaintner K., Ridker P.M.Hum. Mol. Genet. 13:389-396(2004)
Purity	Greater than 90% as determined by SDS-PAGE.
Storage Buffer	Tris-based buffer, 50% glycerol
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function	Participates in at least several B-cell activation processes as well as of other cell types
Involvement in disease	Ischemic stroke (ISCHSTR)
Subcellular Location	Secreted
Protein Families	IL-4/IL-13 family
Paythway	Jak-STATsignalingpathway

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