Tumor Necrosis Factor Ligand Superfamily Member 12 (TNFSF12) Antibody

TNFSF12 Antibody is a Rabbit Polyclonal antibody against TNFSF12. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.

Affinity purified.

O43508

TNFSF12

Calculated MW: 27 kDa, 36 kDa
Observed MW: 25 kDa

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