ALDH18A1 Antibody

ALDH18A1 Antibody is a Rabbit Polyclonal antibody against ALDH18A1. This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.

Image Legend: Fig. 1. Western blot analysis of extracts of various cell lines, using ALDH18A1 antibody.

Unconjugated

Affinity purified.

P54886

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

This product is for research use only.