CBX1 Antibody

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family .The protein is enriched in the heterochromatin and associated with centromeres.The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins.The protein may play an important role in the epigenetic control of chromatin structure and gene expression.Several related pseudogenes are located on chromosomes 1, 3, and X.Multiple alternatively spliced variants, encoding the same protein, have been identified.

Image Legend: Fig. 1: Western blot analysis using CBX1 antibody against Hela (1), COS7 (2), NIH/3T3 (3), A431 (4), and C6 (5) cell lysate. Fig. 2: Immunofluorescence analysis of Hela cells using CBX1 antibody (green). Blue: DRAQ5 fluorescent DNA dye. Fig. 3: Flow cytometric analysis of COS7 cells using CBX1 antibody (green) and negative control (purple).

Unconjugated

Aliquot and store at -20 C. Avoid repeated freeze/thaw cycles.

Ascitic fluid containing 0.03% sodium azide.

This product is for research use only.