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PPP4C Antibody Europäischer Partner

ArtNr abx027585-100
Hersteller Abbexa
Menge 100 ul
Typ Antibody Primary
Applikationen IHC
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products PPP4C
Lieferbar
Description
Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, tumor necrosis factor (TNF) alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair. Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity).
Antigen
PPP4C
Conjugation
Unconjugated
Immunogen
Human PPP4C.
Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody.
Storage
Aliquot and store at -20 C. Avoid repeated freeze/thaw cycles.
Swiss Prot
P60510
Buffer
PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Lead Time
Shipped within 5-10 working days.
Note
This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

 
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