LOST1 Polyclonal Antibody

ArtNr	ABK-ABP54622-100ul
Hersteller	Abbkine Scientific
Menge	100 ul
Quantity options	100 ul 200 ul 30 ul
Kategorie	Oncology Antibodies By Cell Type Hematology Leukemia Sarcoma Myelofibrosis Western Blot ELISA Immunofluorescence Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IF, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	TUSC5,IFITMD3,LOST1,Tumor suppressor candidate 5,Dispanin subfamily B member 1,DSPB1,Interferon-induced transmembrane domain-containing protein D3,Protein located at seventeen-p-thirteen point three 1
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Manufacturer - Applications	Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
Shipping Temperature	Gel pack with blue ice.
Storage Conditions	Stable for one year at -20C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Background	TUSC5 (tumor suppressor candidate 5), also known as protein located at seventeen-p-thirteen point three 1, LOST1 or IFITMD3 (interferon-induced transmembrane domain-containing protein D3), is a 177 amino acid multi-pass membrane protein that belongs to the CD225 family. Thought to play a role in fat metabolism, TUSC5 is highly expressed in mammary gland, heart, smooth muscle, skeletal muscle and stomach, with lower levels found in lung and brain. The gene encoding TUSC5 maps to human chromosome 17, which comprises over 2. % of the human genome and encodes over 1, 200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, and is liked to predisposition of cancers of the ovary, colon, prostate gland and fallopian tubes.
Formulation	Liquid solution
Immunogen	Synthesized peptide derived from the N-terminal region of human LOST1 at AA rangle: 10-90
Precautions	The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration	1 mg/ml
Other information	LOST1 Polyclonal Antibody detects endogenous levels of LOST1 protein.
Storage Buffer	PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.

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Menge: 100 ul

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Lieferung vsl. bis 01.01.2026

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