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NR3C1 Antibody

ArtNr ABC-AM2187b-ev
Hersteller Abcepta
Menge 80 ul
Kategorie
Typ Antibody Monoclonal
Applikationen WB
Clon 740CT12.1.5
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Mouse
Isotype IgM Kappa
Citations Hollenberg S.M., et al. Nature 318:635-641(1985).
Encio I.J., et al. J. Biol. Chem. 266:7182-7188(1991).
Wang W., et al. Nucleic Acids Res. 39:44-58(2011).
Turner J.D., et al. Ann. N. Y. Acad. Sci. 1095:334-341(2007).
Munroe D.G., et al. Submitted (SEP-1993) to the EMBL/GenBank/DDBJ databases.
NCBI NP_000167.1,NP_001018084.1,NP_001018085.1,NP_001018086.1,NP_001018087.1,NP_001018661.1,NP_001019265.1,NP_001191187.1,NP_001191188.1,NP_001191189.1,NP_001191190.1,NP_001191191.1,NP_001191192.1,NP_00119
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Glucocorticoid receptor,GR,Nuclear receptor subfamily 3 group C member 1,NR3C1,GRL
Lieferbar
Manufacturer - Category
Crown Antibodies; Primary Antibodies; Cancer; Signal Transduction; Mitochondrion
Manufacturer - Targets
This NR3C1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 136-164 amino acids from human NR3C1.
Bio Background
Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation. Involved in nuclear translocation (By similarity).
Clonality
Monoclonal
Gene Name
NR3C1
Subtitle
Mouse Monoclonal Antibody (Mab)
Reactivity
H, M
Calculated Molecular Weight
85659
Antigen Region
136-164
Formulation
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
Dilution
WB: 1:1000
Antigen Type
Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 80 ul
Lieferbar: In stock
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