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EGF Antibody (Center)

EGF Antibody (Center)

ArtNr	ABC-AP12878c-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Oncology Neuroscience Neural Signaling Antibodies By Cell Type Carcinoma Cell Biology Cell Culture Cytokines Immunohistochemistry Western Blot
Typ	Antibody Polyclonal
Applikationen	WB, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Citations	de Diesbach, M.T., et al. Exp. Cell Res. 316(19):3239-3253(2010) Xu, Z., et al. Biochem. Biophys. Res. Commun. 401(3):376-381(2010) Lupien, M., et al. Genes Dev. 24(19):2219-2227(2010) Hommel, U., et al. J. Mol. Biol. 227(1):271-282(1992) Hernandez-Sotomayor, S.M., et al. J. Membr. Biol. 128(2):81-89(1992)
NCBI	NP_001171601.1,NP_001171602.1,NP_001954.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Pro-epidermal growth factor,EGF,Epidermal growth factor,Urogastrone,EGF
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Manufacturer - Category	Primary Antibodies; Cancer; Cell Biology; Signal Transduction; Catalog Updated
Manufacturer - Targets	This EGF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 690-720 amino acids from the Central region of human EGF.
Bio Background	This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB16555
Gene Name	EGF
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Calculated Molecular Weight	133994
Antigen Source	HUMAN
Antigen Region	690-720
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000 WB: 1:2000 IHC-P: 1:10~50 IHC-P: 1:25 IHC-P: 1:25
Antigen Type	Synthetic Peptide

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