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Phospho-PIK3R2(Y464) Antibody

ArtNr ABC-AP3494a-ev
Hersteller Abcepta
Menge 80 ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, Dot
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations Khan, N.A., et al., J. Neurovirol. 9(6):584-593 (2003).
Deregibus, M.C., et al., J. Biol. Chem. 277(28):25195-25202 (2002).
Cook, J.A., et al., J. Immunol. 169(1):254-260 (2002).
Park, I.W., et al., Blood 97(2):352-358 (2001).
Zauli, G., et al., FASEB J. 15(2):483-491 (2001).
NCBI NP_005018.1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Phosphatidylinositol 3-kinase regulatory subunit beta,PI3-kinase regulatory subunit beta,PI3K regulatory subunit beta,PtdIns-3-kinase regulatory subunit beta,Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta,PI3-kinase subunit p85-beta,PtdIns-3-kinase regulatory subunit p85-beta,PIK3R2
Lieferbar
Manufacturer - Category
Primary Antibodies; Antibody Collections; Cancer; Cell Biology; Immunology; Signal Transduction; Phospho Antibodies
Manufacturer - Targets
This PIK3R2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y464 of human PIK3R2.
Bio Background
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.PIK3R2 binds to activated Protein Tyrosine Kinases, which are phosphorylated, through its SH2 domain, and acts as an adaptor, mediating the association of the P110 catalytic unit to the plasma membrane.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB13728
Gene Name
PIK3R2
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Predicted Reactivity
B, M, Rat
Calculated Molecular Weight
81545
Antigen Source
HUMAN
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
WB: 1:1000
DB: 1:500
Antigen Type
Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 80 ul
Lieferbar: In stock
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