M-CSF Receptor

Hersteller Abclonal
Kategorie
Typ Antibody Polyclonal
Specific against Human
Applikationen WB, FC
Protein Familie Tyrosine Kinase
Menge 100ug
Host Rabbit
ArtNr A0736
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
*

DESCRIPTION

Calculated MW
108kDa
Immunogen
Recombinant protein of human CSF1R
Gene ID
1436
Swiss Prot
P07333
Synonyms
FMS; CSFR; FIM2; HDLS; C-FMS; CD115; CSF-1R; M-CSF-R;
Isotype
IgG
Purity
Affinity purification
Storage Buffer
Store at 4? or -20?. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background
The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction.
Recommended Dilutions
WB 1:500-1:1000 IF 1:20-1:50 FC 1:20-1:50
illustration
Western blot analysis of extracts of K562 celllines, using CSF1R antibody.

Arbeitsanleitung

A0736.pdf

Menge: 100ug
Lieferbar: In stock
Listenpreis: 289,30 €
Preis: 289,30 €
lieferbar

Vergleichen

Angebot anfordern

Fragen zum Produkt?

Ihr Ansprechpartner:

Arne Pelz

sales@hoelzel.de