PKR

Hersteller Abclonal
Kategorie
Typ Antibody Polyclonal
Specific against Human, Mouse
Applikationen WB, IHC
Protein Familie Translational Control
Menge 100ug
Host Rabbit
ArtNr A0472
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
*

DESCRIPTION

Calculated MW
62kDa
Immunogen
A synthetic peptide of human EIF2AK2
Gene ID
5610
Swiss Prot
P19525
Synonyms
PKR; PRKR; EIF2AK1;
Isotype
IgG
Purity
Affinity purification
Storage Buffer
Store at 4? or -20?. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.
Recommended Dilutions
WB 1:500-1:1000 IHC 1:50-1:100
illustration
Western blot analysis of extracts of HepG2 celllines, using EIF2AK2antibody.

Arbeitsanleitung

A0472.pdf

Menge: 100ug
Lieferbar: In stock
Listenpreis: 289,30 €
Preis: 289,30 €
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Ihr Ansprechpartner:

Arne Pelz

sales@hoelzel.de