CCR5

Hersteller Abclonal
Kategorie
Typ Antibody Polyclonal
Specific against Human, Mouse, Rat
Applikationen WB
Menge 100ug
Host Rabbit
ArtNr A1298
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Calculated MW
41kDa
Immunogen
Fusion protein of human CCR5
Synonyms
CC-CKR-5, CCCKR5, CD195, CKR-5, CKR5, CMKBR5, FLJ78003, IDDM22
Purity
Affinity purification
Storage Buffer
Store at -20C or -80C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background
C-C or ? chemokine family members are characterized by a pair of adjacent cysteine residues and serve as potent chemoattractants and activators of monocytes and T cells. C-C chemokine receptor family members include CKR-1, CKR-2A, CKR-2B, CKR-3, CKR-4, CKR-5, CKR-6, CKR-7, CKR-8, CKR-9, CKR-10 and the Duffy blood group antigen. Each of these receptors are G protein-coupled, seven pass transmembrane domain proteins whose major physiological role is to function in the chemotaxis of T cells and phagocytic cells to areas of inflammation. However, this receptor family has also been shown to facilitate viral infection. Termed a “coreceptor”, CKR-5, along with CD4, has been shown to be a major receptor for HIV. CKR-5 tends to associate with macrophage-tropic viruses, such as macrophage tropic HIV-1, while CKR-2B and CKR-3 bind a minority of viruses.
Illustration
Western blot analysis of HeLa cell and K-562cell lysate using CCR5 antibody.
Gene Symbol
CCR5
GeneID (Human)
1234
GeneID
1234
Protein MW
352
SWISS
P51681
Route
Recombinant Protein
Menge: 100ug
Lieferbar: In stock
lieferbar
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