Capan-1 cells

ArtNr	C0018001
Hersteller	Addexbio
Menge	One Frozen vial
Kategorie	Oncology Metabolism Diabetes Cell Lines & Cell Culture Cell Lines By Organ Skin Cancer Breast Cancer Pancreatic Cancer
Typ	Tumour Cells
Specific against	Human (Homo sapiens)
Dry ice	Yes
Citations	1.Holt, J. T., Toole, W. P., Patel, V. R., Hwang, H., and Brown, E. T. Restoration of CAPAN-1 cells with functional BRCA2 provides insight into the DNA repair activity of individuals who are heterozygous for BRCA2 mutations. Cancer Genet Cytogenet, 186: 85-94, 2008. 2.Fanjul, M., Alvarez, L., and Hollande, E. Expression and subcellular localization of a 35-kDa carbonic anhydrase IV in a human pancreatic ductal cell line (Capan-1). J Histochem Cytochem, 55: 783-794, 2007. 3.Szucs, A., Demeter, I., Burghardt, B., Ovari, G., Case, R. M., Steward, M. C., and Varga, G. Vectorial bicarbonate transport by Capan-1 cells: a model for human pancreatic ductal secretion. Cell Physiol Biochem, 18: 253-264, 2006. 4.Liu, Z. W., Zhao, Y. P., Liao, Q., Wu, Y. D., and Zhu, Y. [Relationship between apoptosis induced by 2-butylamino-2-demethoxy-hypocrellin B in human pancreatic cancer cells Capan-1 and photosensitization of mitochondria]. Zhonghua Wai Ke Za Zhi, 44: 36-39, 2006. 5.Gay, M., Montana, A. M., Moreno, V., Prieto, M. J., Llorens, R., and Ferrer, L. Studies of interaction of dichloro[eta2-dimethyl-(2-methylidene-cyclohexylmethyl)-amino]platinum(II) with DNA: effects on secondary and tertiary structures of DNA - cytotoxic assays on human cancer cell lines Capan 1 and A431. J Inorg Biochem, 99: 2387-2394, 2005. 6.McCabe, N., Lord, C. J., Tutt, A. N., Martin, N. M., Smith, G. C., and Ashworth, A. BRCA2-deficient CAPAN-1 cells are extremely sensitive to the inhibition of Poly (ADP-Ribose) polymerase: an issue of potency. Cancer Biol Ther, 4: 934-936, 2005. 7.Shirk, A. J. and Kuver, R. Epidermal growth factor mediates detachment from and invasion through collagen I and Matrigel in Capan-1 pancreatic cancer cells. BMC Gastroenterol, 5: 12, 2005.
ECLASS 10.1	32160890
ECLASS 11.0	32160890
UNSPSC	41106509
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Description	Disease: Pancreatic adenocarcinoma Origin: Established from liver Species: Homo sapiens Tissue: Pancreas Morphology: Epithelial Properties: Adherent fibroblastic semi-confluent monolayer forming loosely adherent foci Cytogenic data: Tumorigenic; hypotriploid with abnormalities Patient: Male, Caucasian, 40 yrs of age Medium: IMDM + 20% FBS Subculture: 1:2 to 1:4 using 0.25% trypsin or trypsin/EDTA, 5% CO2; 37C Freezing Medium: Complete culture medium supplemented with 5% (v/v) DMSO Biosafety Level: I Sterility: Bacteria: Negative Yeast: Negative Mycoplasma: Negative Pathogens: HIV: Negative Hepatitis B: Negative Hepatitis C: Negative Protein Expression: mucin, progesterone receptor, estrogen receptor alpha, HLA A2, A9, B13, B17 Isoenzymes: AK-1, 1; ES-D, 1; G6PD, B; GLO-I, 1-2; Me-2, 1; PGM1, 1-2; PGM3, 1; DNA Profile (STR): Amelogenin: X; CSF1PO: 11; D13S317: 9; D16S539: 13, 14; D5S818: 11; D7S820: 10, 11; THO1: 6; TPOX: 8, 11; vWA: 16 Mutations in Capan-1 Cells Related cells by Organ: AR-42J cells BxPc-3 cells Capan-1 cells MIA PaCa-2 cells E3LZ10.7 cells A10.7 cells INS-1 cells MIN-6 cells
Storage condition	LN2
Manufacturer - Category	Cell Lines

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