Cytokeratin/Keratin 20

The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21.

Optimal dilution should be determined by user

K20, CD20, CK20, CK-20, KRT21

When reconstituted with 175ul H20 dist, a final solution volume of 250 ul will contain 30mM Tris/HCl, pH 8.0, 9.5M urea, 2mM DTT, 2 mM EDTA, 10 mM Methylammoniumchloride, with a protein concentration of 1mg/ml

Escherichia coli

pI 5.66