Cytokeratin/Keratin 19

The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21

Optimal dilution should be determined by user

CK19, K19, K1CS

When reconstituted with 70ul H20 dist, a final solution volume of 100 ul will contain 30mM Tris/HCl, pH 8.0, 8M urea, 2mM DTT, 0.1 mM na-EDTA with a protein concentration of 1mg/ml (according to protein dry weight).

Escherichia coli

pI 5.1