GC-Globulin

An alpha 2 glycoprotein composed of a single polypeptide chain and present in plasma at levels of 20-55 mg/100ml. It functions in the binding and transport of vitamin D and may also play an important role in actin homeostatis since it has been shown to bind monomeric actin. GC Globulin also binds membranes of both circulating B and T lymphocytes. Clinically concentrations are reduced in patients with severe liver diseases. GC Globulin may also play an important role in the mechanism of the osteomalacia that occurs with Itai-Itai disease.

2-8C for immediate use, or at -20C (aliquot)

Human plasma. Nonreactive and negative for HBsAg, anti-HCV, anti-HBc, and anti-HIV by FDA-required tests