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Immunoglobulin M, Fc5mu

ArtNr ARP-13-3035-3
Hersteller American Research Products
Menge 200 ug
Kategorie
Typ Proteins Native
Specific against other
Purity >95% by SDS-PAGE . No reaction by IEP to antisera to kappa or lambda
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias IgM
Lieferbar
Description
Purified Native Human Immunoglobulin M Fc5mu (IgM-Fc5mu). The FC portion of the IgM molecule is important for structural studies and is thought to influence complement fixation and placental permeability.
Background
Immunoglobulin M (IgM) is a basic antibody that is produced by B cells. IgM is by far the physically largest antibody in the human circulatory system. IgM forms polymers where multiple immunoglobulins are covalently linked together with disulfide bonds, mostly as a pentamer but also as a hexamer. IgM has a molecular mass of approximately 970 kDa (in its pentamer form). Because each monomer has two antigen binding sites, a pentameric IgM has 10 binding sites.
Form
Purified, in 20 mM phosphate, pH 7.4 with 150 mM NaCl
Synonyms
IgM
Purity
>, 95% by SDS-PAGE . No reaction by IEP to antisera to kappa or lambda
Source
  • Human plasma. Blood sample from donors was tested and found negative
  • for HBsAg, HIV-1&, 2 antibodies, HCV and Syphilis
Notes
Because no test method can offer complete assurance that products derived from human source will not transmit infectious agents, it is recommended that this product be handled with the same precautions used for patient specimens.
Molecular Weight
342000

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200 ug
Lieferbar: In stock
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