Vitronectin

ArtNr	ARP-13-3057
Hersteller	American Research Products
Menge	100 ug
Kategorie	Peptides & Proteins Native Proteins
Typ	Proteins Native
Specific against	other
Purity	>95% by SDS-PAGE
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	VTN, VN, V75, VNT
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Description	Vitronectin and plasminogen activator inhibitor type 1 are proteins that interact in the circulatory system and pericellular region to regulate fibrinolysis, cell adhesion, and migration. Plasminogen activator inhibitor type 1, a serine proteinase, through its binding to the plasma protein vitronectin, influences processes that are key regulators of hemostatic process, for example, thrombosis and wound healing. In addition the vitronectin and plasminogen activator inhibitor type 1 complex regulates binding of blood platelets and cells to extracellular substrata in events like tumor metastasis. The plasma concentration of vitronectin is 200 to 400 I¼g/ml
Background	The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.
Form	Lyophilized, in 10 mM sodium phosphate, pH 7.7
Storage	2-8C for immediate use, or at -20C (aliquot)
Synonyms	VTN, VN, V75, VNT
Purity	>, 95% by SDS-PAGE
Source	Human plasma. Blood sample from the tissue donors was tested and found negative for HBsAg, HIV-1&, 2 antibodies, HCV and Syphilis
Notes	Because no test method can offer complete assurance that products derived from human source will not transmit infectious agents, it is recommended that this product be handled with the same precautions used for patient specimens.
Molecular Weight	75000

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Menge: 100 ug

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Lieferung vsl. bis 18.12.2025

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