SensoLyte® 490 MMP-2 Assay Kit Fluorimetric - 1 kit

FRET; Protease activity

Matrix Metalloproteinase (MMP), MMP-2

Store all components at -20°C. Protect components A and B from light. Components D and E can be stored at 4 °C for convenience.

Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated proteins capable of digesting extracellular matrix components. The importance of MMPs in tumor development and invasion is well known. MMP-2 (gelatinase A) is proposed as a potential therapeutic target.
The SensoLyte® 490 MMP-2 Assay Kit is a complete assay system designed to continuously analyze MMP activities or to screen MMP-2 inhibitors by using a fluorogenic MMP-2 substrate.
Members of the MMP family have poor substrate sequence specificity, making it difficult to use a peptide substrate alone to differentiate the activity of a particular MMP from other MMPs. If several MMPs are coexisting in your samples and you would like to specifically measure MMP-2 activity, please choose the SensoLyte® Plus MMP-2 Assay Kit, Cat# AS-72224.

340

Fluorescent

Research use

5400535133139