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Recombinant rat MOG (1-125)

Recombinant rat MOG (1-125)

ArtNr	AS-55152-500
Hersteller	AnaSpec
Menge	500 ug
Kategorie	Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience In Vivo Peptides & Proteins Recombinant Proteins Western Blot ELISA Immunostaining Microglia Markers
Typ	Proteins Recombinant
Format	Liquid
Applikationen	WB, ELISA, IV
Specific against	other
Host	E.coli
Konjugat/Tag	Unconjugated
Purity	≥95% by SDS-PAGE
Dry ice	Yes
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Versandbedingung	Trockeneis
Lieferbar
Manufacturer - Type	Catalog recombinant
Manufacturer - Applications	in vivo studies; Western Blotting; ELISA
Manufacturer - Category	Catalog Recombinant Proteins / Catalog Recombinant / Proteins
Manufacturer - Targets	Myelin Oligodendrocyte Glycoprotein (MOG)
Shipping Temperature	Dry Ice
Storage Conditions	Store at -80°C. Avoid repeated freeze-thaw cycles.
Molecular Weight	14.2 kDa
Manufacturer - Research Area	Neuroscience / Multiple Sclerosis
Description	Myelin Oligodendrocyte Glycoprotein (MOG) is a member of the immunoglobulin superfamily and is expressed exclusively in the central nervous system (CNS). Although MOG protein constitutes only 0.01-0.05% of the CNS myelin proteins, it was demonstrated that MOG protein is a crucial autoantigen for multiple sclerosis in humans and experimental autoimmune encephalomyelitis (EAE) in rodents and monkeys - The sequence (Accession #CAE84068) corresponding to the extracellular domain of rat MOG along with a 6x His tag was expressed in E. coli. The recombinant rat MOG (R-rMOG) was purified from urea denatured bacterial lysate using immobilized metal affinity chromatography (IMAC). The molecular mass of the recombinant rat MOG is 14.2 kDa.
Purification Method	Purified
Concentration	1 mg/ml
Storage Buffer	25 mM sodium acetate buffer (pH=4.0)
Manufacturer - Specificity	rat MOG
Post Synthesis Coupling	No
Resuspension Condition	rat MOG must be thoroughly mixed directly with Complete Freund’s Adjuvant (CFA). Do not dilute recombinant rat MOG with buffers that have pH greater than 4.5. Protein will precipitate at pH higher than 4.5
Usage	Research use
UNSPSC	12352202
GTIN	5400535012403

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AS-55152-500-safety-datasheet.pdf