Mouse Monoclonal Antibody to MATK

Catalog Number: sAP-0321
Product Name: Mouse Monoclonal Antibody to MATK
Target Molecle: MATK
Aliases: CHK; CTK
Species: Human
MW: 56kDa
Enterez GeneID: 4145
General Information: MATK (megakaryocyte-associated tyrosine kinase), also known as CTK, this protein has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.
Immunogen: Purified recombinant fragment of human MATK expressed in E. Coli.
Clone: MM9D7;
Isotype: Mouse IgG1
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Antibody are purified by protein G affinity chromatography. ; Liquid in PBS containing 50% glycerol and 0.03% sodium azide. ;
Reconstitution and Storage: Reconstitued with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000; FCM: 1 to 200 - 1 to 400
References: 1. Cell. 1997 Jun 27; 89(7):1067-76. ; 2. Biochem Biophys Res Commun. 2000 Dec 9; 279(1):6-10. ; 3. Proc Natl Acad Sci U S A. 2004 Aug 17; 101(33):12130-5.