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ATF4 Antibody - C-terminal region

ArtNr ARP38067_T100-25UL
Hersteller AVIVA Systems Biology
Menge 25 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Guinea Pig, Sheep (Ovine, Ovis aries), Dog (Canine, Canis lupus familiaris), Horse (Equine), Yeast (Saccharomyces cerevisiae), Cow (Bos taurus)
Host Rabbit
Sequence EQNKTAATRYRQKKRAEQEALTGECKELEKKNEALKERADSLAKEIQYLK
Citations Exclusion of the unfolded protein response in light-induced retinal degeneration in the canine T4R RHO model of autosomal dominant retinitis pigmentosa. PLoS One. 10, e0115723 (2015). 25695253
Lassot,I., et al., (2005) J. Biol. Chem. 280 (50), 41537-41545
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias CREB2,TXREB,CREB-2,TAXREB67
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Transcription Factor, Root Catalog/Products/Polyclonal Antibodies/Transcription Regulation, Root Catalog/Research Areas/DNA\/RNA\/Protein Interactions, Root Catalog/Research Areas/Transcription Factors, Root Catalog/Products/Polyclonal Antibodies/Trial Size Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies, Root Catalog/Products/Aviva Rabbit Polyclonal
Shipping Temperature
Wet Ice
Molecular Weight
39kDa
Species Tested
Human
Gene symbol
ATF4
Gene Fullname
Activating transcription factor 4 (tax-responsive enhancer element B67)
Protein size
351
Product format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and storage
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins
GPS2; GOLGA1; EP300; CEBPG; GOLGA8F; GOLGA8EP; GCC1; TRIB3; CCDC106; LDOC1; FBXW11; NDC80; BTRC; BFSP2; DDIT3; CREBBP; NEK6; JUN; FOS; ATF2; CEBPE; CEBPA; ATF4; ATF3; BATF2; CREBZF; BATF3; BATF; CREB3; MAFB; FOSL1; NFE2L2; NFE2; MAF; UBC; TGM2; RPS6; MAP2
Description of target
ATF4s a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication.
Nucleotide accession_num
NM_001675
Protein accession_num
NP_001666
Protein name
Cyclic AMP-dependent transcription factor ATF-4
Clonality
Polyclonal
Purification
Protein A purified
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human ATF4
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rat: 93%; Sheep: 93%; Yeast: 82%
Concentration
1.0 mg/ml
Sample Type Confirmation

ATF4 is supported by BioGPS gene expression data to be expressed in Jurkat

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 25 ul
Lieferbar: In stock
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