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CD11a(DF1524), CF740 conjugate, 0.1mg/mL

ArtNr B-BNC740312-100
Hersteller Biotium
Menge 100 uL
Kategorie
Typ Antibody Monoclonal
Applikationen FC, IF
Clon DF1524
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2b Kappa
Citations J Neuropathol Exp Neurol (2000) 59(1): 18-28. (functional studies)FASEB J (2003) 17(11), 1-21. (Flow)Blood (2006) 107(8): 3212-3220. (IF)
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Antigen CD11A (p180),lymphocyte function associated antigen 1,alpha polypeptide,Integrin alpha-L,ITGAL,Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain,LFA 1 alpha (LFA1A),Ly15,Ly21,p180
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Primary
Manufacturer - Applications
Flow, surface (published), Functional studies (published), IF (published)
Manufacturer - Category
Primary Antibodies Only
Manufacturer - Targets
CD11a
Manufacturer - Conjugate / Tag
CF740
Manufacturer - Host
Mus musculus (mouse), Bos taurus (bovine)
Shipping Temperature
Room Temperature (Next day)
Storage Conditions
Store at 2 to 8°C|Protect fluorescent conjugates from light
Molecular Weight
180 kDa
Manufacturer - Research Area
Immunology
Description
Recognizes a protein of 180 kDa, identified as CD11a (Leucocyte Workshop IV; Code 1524). CD11a complex with the 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a /C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses. This MAb potently blocks LFA-1 dependent homotypic cell aggregation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product origin
Animal
Ingredient of biological origin
Mus musculus (mouse), Bos taurus (bovine)
Special handling for PI and label
Protect from light
Undated stability guarantee in PI
2 years
Stability at RT during shipping (protected from light)
Stable at room temperature or 37°C (98°F) for 7 days.
UNSPSC Commodity
41116161
UNSPSC Commodity Title
Primary and secondary antibodies for multiple methodologyimmunostaining detection application
Classified or regulated chemicals
0.05% sodium azide (CAS 26628-22-8)
Concentration
0.1 mg/mL
Storage buffer
PBS, 0.1% rBSA, 0.05% azide
Dated shelf life printed on label
Guaranteed for at least 24 months from date of receipt when stored as recommended
Immunogen (Secondaries, for anti tag only)
Human CD11a protein
Clonality
Monoclonal
Regulatory Status
For research use only (RUO)
Human Gene Symbol
ITGAL
Unigene
174103
Positive Control
JY, HUT-78, MOLT-4, HL60, U937, and human leukocytes. Human lymph nodes and tonsils.
Antibody target cellular localization
Plasma membrane
Cell tissue expression
Hematopoietic cells
Antibody applications
Flow, surface (published)|Functional studies (published)|IF (published)
Antibody application notes
Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Immunofluorescence: 0.5-1 ug/mL|Flow Cytometry 0.5-1 ug/million cells/0.1 mL
Expected Antibody Applications
Flow, surface (published for clone), Functional studies (published for clone), IF (published for clone)
Manufacturer - Antibody Reactivity
CD11a
Antibody number
#0312

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 uL
Lieferbar: In stock
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