BCL10 (MALT-Lymphoma Marker) (BL10/2988R), CF740 conjugate, 0.1mg/mL

Primary

Primary Antibodies Only

CF740

Room Temperature (Next day)

33 kDa

B-cell lymphoma/leukemia 10 (BCL10) is a signaling protein that promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK. BCL10 contains an N-terminal caspase recruitment domain (CARD), which is found in a number of apoptotic regulatory molecules. BCL10 is involved in the adaptive immune response, and may be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. A BCL10 translocation is recurrent in low-grade mucosa-associated lymphoid tissue (MALT lymphoma).Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Oryctolagus cuniculus (domestic rabbit), Bos taurus (bovine)

2 years

41116161

0.05% sodium azide (CAS 26628-22-8)

PBS, 0.1% rBSA, 0.05% azide

Recombinant human BCL10 protein fragment (around aa122-168) (exact sequence is proprietary)

For research use only (RUO)

193516

Nucleus & cytoplasm

Flow (intracellular) (verified)|IF (verified)|IHC (FFPE) (verified)

BCL10