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Anti-Beta4-Spectrin Antibody

ArtNr 73-376
Hersteller Antibodies Incorporated
Menge 5 mL
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, IHC, ICC
Clon N393/2
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG1
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Spectrin beta chain, non-erythrocytic 4 (Beta-IV spectrin) (Spectrin, non-erythroid beta chain 3)
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibody
Manufacturer - Targets
Beta4-spectrin
Country of Origin
United States
Shipping Temperature
Shipped on ice packs
Storage Conditions
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight
>200 kDa
Manufacturer - Research Area
Cell Markers, Neuronal Markers, Axonal Markers, Scaffold Proteins
Expiration
24 months from date of receipt
Immunogen
Fusion protein amino acids 1621-1832 (C-terminal repeats 14 to 15) of human Beta4-spectrin (accession number Q9H254) produced recombinantly in E. Coli
Immunogen Species
Human
Description
Our Anti-Beta4-spectrin mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N393/2. It detects human, mouse, and rat Beta4-spectrin, and is TC supernatant. It is great for use in IHC, ICC, WB.
Target Description
Spectrin beta chain, non-erythrocytic 4, or ß4 spectrin, is a member of the spectrin family of cytoskeletal proteins. It is found in the cytoskeleton and cell cortex of cells in the brain and pancreatic islets. It is also expressed in skeletal muscule. ß4 spectrin functions as a scaffold protein that links the actin cytoskeleton to the plasma membrane. It is involved in cell shape and organization. Mutations in the ß4 spectrin gene are associated with congenital myopathy, and neurodevelopmental disorder with hypotonia, neuropathy and deafness (NEDHND).
Clonality
Monoclonal
Manufacturer - Specificity
Does not cross-react with other Beta-spectrins
Concentration
Lot dependent
Form
TC Supernatant
Buffer
Supernatant is provided in cell culture medium with 0.1% sodium azide as anti-microbial
Production Notes
Supernatant is harvested from hybridoma cells grown under standard cell culture conditions
Quality Control
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
Quality Control: Application
WB Brain
Dilution Range: IHC
1:500
Dilution Range: ICC
1:500
Usage Statement
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement
We produce our Beta4-spectrin mouse monoclonal primary antibody from hybridoma clone N393/2. It is great in IHC, ICC, WB and is TC supernatant.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 5 mL
Lieferbar: In stock
lieferbar

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