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Anti-Kv4.2 Potassium Channel Antibody

ArtNr 75-361
Hersteller Antibodies Incorporated
Menge 100 uL
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, IHC, ICC
Clon L28/4
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG1
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Potassium voltage-gated channel subfamily D member 2 (RK5) (Shal1) (Voltage-gated potassium channel subunit Kv4.2)
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibody
Manufacturer - Targets
Kv4.2 potassium channel
Country of Origin
United States
Shipping Temperature
Shipped on ice packs
Storage Conditions
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight
70 kDa
Manufacturer - Research Area
Ion Channels and Modulators, K+ Channels
Expiration
24 months from date of receipt
Immunogen
Fusion protein amino acids 471-630 (cytoplasmic C-terminus) of rat Kv4.2 (accession number Q63881) produced recombinantly in E. Coli
Immunogen Species
Rat
Description
Our Anti-Kv4.2 potassium channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L28/4. It is KO validated, detects human, mouse, and rat Kv4.2 potassium channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
Target Description
Potassium voltage-gated channel subfamily D member 2 or Kv4.2 potassium channel subunit is encoded by the gene KCND2. Kv4.2 is an alpha subunit of the voltage-gated potassium channel (Shal) family and mediates transmembrane potassium transport in excitable membranes. Kv4.2 is an integral membrane protein that combines to form tetramers. Kv4.2 is detected in the heart and brain. In brain it is found at the cell junction, synapse, postsynaptic cell membrane. Diseases associated with this gene include Cycloplegia and early myoclonic encephalopathy.
Clonality
Monoclonal
Manufacturer - Specificity
Does not cross-react with Kv4.3 (based on KO validation results)
Concentration
1 mg/mL
Form
Purified by Protein A chromatography
Buffer
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Production Notes
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
Quality Control: Application
WB Brain
Dilution Range: WB
1:500
Dilution Range: IHC
1:100
Usage Statement
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement
We produce our Kv4.2 potassium channel mouse monoclonal primary antibody from hybridoma clone L28/4. It is great in IHC, ICC, WB and is purified by Protein A chromatography.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 uL
Lieferbar: In stock
lieferbar

Lieferung vsl. bis 11.09.2025 

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