Anti-TRIP8B (Exon 1A/5 Junction) Antibody

TRIP8b (exon 1a/5 junction)

Shipped on ice packs

60 kDa

24 months from date of receipt

Mouse

PEX5-related protein, Peroxisomal Biogenesis Factor 5 Like, TPR-containing Rab8b-interacting protein or TRIP8b is encoded by the gene Pex5l. It is a member of the peroxisomal targeting signal receptor family. TRIP8b is a cytoplasmic accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. TRIP8b interacts with the carboxyl-terminal region of HCN channels and regulates their cell-surface expression to the dendrites in many types of neurons. TRIP8b plays a role in regulation of HCN channel cyclic nucleotide kinetics. TRIP8b is expressed in the brain. Diseases associated with PEX5L include Rhizomelic Chondrodysplasia Punctata, Type 5 and Rhizomelic Chondrodysplasia Punctata, Type 2.

Specific for exon 1a/5 junction (does not react

Purified by Protein A chromatography

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

ICC

We produce our TRIP8b (exon 1a/5 junction) mouse monoclonal primary antibody from hybridoma clone N291C/22. It is great in ICC, WB and is purified by Protein A chromatography.