Vergleich

Anti-TASK1 Potassium Channel Antibody

ArtNr 75-357
Hersteller Antibodies Incorporated
Menge 100 uL
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, IHC, ICC
Clon N374/48
Specific against Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG2b
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1) (Two pore K(+) channel KT3.1)
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibody
Manufacturer - Targets
TASK1 potassium channel
Country of Origin
United States
Shipping Temperature
Shipped on ice packs
Storage Conditions
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight
50 kDa
Manufacturer - Research Area
Ion Channels and Modulators, K+ Channels
Expiration
24 months from date of receipt
Immunogen
Fusion protein amino acids 251-411 (cytoplasmic C-terminus) of rat Acid-sensitive potassium channel protein TASK or TASK1 (accession number O54192) produced recombinantly in E. Coli
Immunogen Species
Rat
Description
Our Anti-TASK1 potassium channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N374/48. It is KO validated, detects mouse and rat TASK1 potassium channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
Target Description
Potassium two pore domain channel subfamily K member 3 is encoded by the gene KCNK3. KCNK3 is a member of the two pore domain potassium channel (TC 1.A.1.8) family. KCNK3 is a pH dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from the potassium ion concentration on either side of the membrane, with it functioning as an outward rectifier when the external potassium concentration is low, and it functioning as an internal rectifier when the external potassium concentration is high. KCNK3 is expressed in the heart, lung, brain, liver, kidney, and skeletal muscle. Diseases associated with KCNK3 include Pulmonary Hypertension Primary 4 and Heritable Pulmonary Arterial Hypertension.
Clonality
Monoclonal
Manufacturer - Specificity
Does not cross-react with TASK3
Concentration
1 mg/mL
Form
Purified by Protein A chromatography
Buffer
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Production Notes
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control
Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.
Quality Control: Application
IHC
Usage Statement
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement
We produce our TASK1 potassium channel mouse monoclonal primary antibody from hybridoma clone N374/48. It is great in IHC, ICC, WB and is purified by Protein A chromatography.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 uL
Lieferbar: In stock
lieferbar

Lieferung vsl. bis 11.09.2025 

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